Medicinal Natural Products: A Biosynthetic Approach, Second Edition
Paul M Dewick(auth.)
Medicinal Natural Products, Second Edition is a comprehensive guide providing information on all classes of natural products in medicine. It builds upon fundamental chemical principles and demonstrates a unique integration of plant, microbial and animal natural products in one volume. The text guides the reader through a wealth of diverse natural metabolites used in medicine with sources, production methods, use as drugs and modes of action all extensively covered. Taking a chemistry based approach it combines traditional pharmacognosy with medicinal chemistry. The structure is user-friendly and includes the acclaimed grey boxes on groups of products and detailed mechanistic explanations.
* Adopts a novel biosynthetic theme rather than a traditional descriptive approach
* Includes extensive further reading at the end of the chapter
* Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products
* Includes the latest developments in the field
* New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids
* User-friendly format including extensive use of chemical schemes with annotated mechanistic explanations Content:
Chapter 1 About this Book, and How to Use it (pages 1–5):
Chapter 2 Secondary Metabolism: The Building Blocks and Construction Mechanisms (pages 7–34):
Chapter 3 The Acetate Pathway: Fatty Acids and Polyketides (pages 35–120):
Chapter 4 The Shikimate Pathway: Aromatic Amino Acids and Phenylpropanoids (pages 121–166):
Chapter 5 The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids (pages 167–289):
Chapter 6 Alkaloids (pages 291–403):
Chapter 7 Peptides, Proteins, and Other Amino Acid Derivatives (pages 405–464):
Chapter 8 Carbohydrates (pages 465–486):
* Adopts a novel biosynthetic theme rather than a traditional descriptive approach
* Includes extensive further reading at the end of the chapter
* Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products
* Includes the latest developments in the field
* New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids
* User-friendly format including extensive use of chemical schemes with annotated mechanistic explanations Content:
Chapter 1 About this Book, and How to Use it (pages 1–5):
Chapter 2 Secondary Metabolism: The Building Blocks and Construction Mechanisms (pages 7–34):
Chapter 3 The Acetate Pathway: Fatty Acids and Polyketides (pages 35–120):
Chapter 4 The Shikimate Pathway: Aromatic Amino Acids and Phenylpropanoids (pages 121–166):
Chapter 5 The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids (pages 167–289):
Chapter 6 Alkaloids (pages 291–403):
Chapter 7 Peptides, Proteins, and Other Amino Acid Derivatives (pages 405–464):
Chapter 8 Carbohydrates (pages 465–486):
Kategoriler:
Yıl:
2002
Yayımcı:
John Wiley & Sons, Ltd
Dil:
english
Sayfalar:
514
ISBN 10:
0471496405
ISBN 13:
9780471496403
Dosya:
PDF, 5.07 MB
IPFS:
,
english, 2002
Bu kitap, telif hakkı sahibinin şikayeti nedeniyle indirilememektedir